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Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID‐19 from influenza pneumonia

OBJECTIVE: Infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can lead to severe pneumonia, but also thrombotic complications and non‐pulmonary organ failure. Recent studies suggest intravascular neutrophil activation and subsequent immune cell–triggered immunothrombosis as...

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Detalles Bibliográficos
Autores principales: Nicolai, Leo, Leunig, Alexander, Brambs, Sophia, Kaiser, Rainer, Joppich, Markus, Hoffknecht, Marie‐Louise, Gold, Christoph, Engel, Anouk, Polewka, Vivien, Muenchhoff, Maximilian, Hellmuth, Johannes C., Ruhle, Adrian, Ledderose, Stephan, Weinberger, Tobias, Schulz, Heiko, Scherer, Clemens, Rudelius, Martina, Zoller, Michael, Keppler, Oliver T., Zwißler, Bernhard, von Bergwelt‐Baildon, Michael, Kääb, Stefan, Zimmer, Ralf, Bülow, Roman D., von Stillfried, Saskia, Boor, Peter, Massberg, Steffen, Pekayvaz, Kami, Stark, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Journal of Thrombosis and Haemostasis published by ELSEVIER INC. on behalf of International Society on Thrombosis and Haemostasis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753335/
https://www.ncbi.nlm.nih.gov/pubmed/33217134
http://dx.doi.org/10.1111/jth.15179