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Disruption of microRNA‐214 during general anaesthesia prevents brain injury and maintains mitochondrial fusion by promoting Mfn2 interaction with Pkm2

Duration of surgical general anaesthesia is associated with severe brain injury and neurological deficits. The specific mechanisms underlying post‐general anaesthesia brain injury, however, still remain to be elucidated. Herein, we explore the role of microRNA‐214 (miR‐214) in the occurrence of brai...

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Detalles Bibliográficos
Autores principales: Liu, Tiejun, Wang, Bin, Li, Gai, Dong, Xiaoliu, Yu, Guannan, Qian, Qingzeng, Duan, Likun, Li, Hongxia, Jia, Zhao, Bai, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753869/
https://www.ncbi.nlm.nih.gov/pubmed/33147380
http://dx.doi.org/10.1111/jcmm.15222