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Low let‐7d exosomes from pulmonary vascular endothelial cells drive lung pericyte fibrosis through the TGFβRI/FoxM1/Smad/β‐catenin pathway

The pathogenesis of pulmonary fibrosis (PF) was mediated by the progressive deposition of excessive extracellular matrix, but little is known about the regulatory mechanisms of fibrogenesis by lung pericytes. The mouse PF model was established by treatment with bleomycin, followed by isolation of ex...

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Detalles Bibliográficos
Autores principales: Xie, Han, Gao, Yuan‐Mei, Zhang, Yong‐Chang, Jia, Ming‐Wang, Peng, Fang, Meng, Qing‐He, Wang, Yi‐Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753874/
https://www.ncbi.nlm.nih.gov/pubmed/33179861
http://dx.doi.org/10.1111/jcmm.15989