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Gene bashing of ceh-6 locus identifies genomic regions important for ceh-6 rectal cell expression and rescue of its mutant lethality

Strong loss-of-function or null mutants can sometimes lead to a penetrant early lethality, impairing the study of these genes’ function. This is the case for the ceh-6 null mutant, which exhibits 100% penetrant lethality. Here, we describe how we used gene bashing to identify distinct regulatory reg...

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Detalles Bibliográficos
Autores principales: Ahier, Arnaud, Suman, Shashi Kumar, Jarriault, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753896/
https://www.ncbi.nlm.nih.gov/pubmed/33364555
http://dx.doi.org/10.17912/micropub.biology.000339