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MicroRNA-1911-3p targets mEAK-7 to suppress mTOR signaling in human lung cancer cells

Regulation of mTOR signaling depends on an intricate interplay of post-translational protein modification. Recently, mEAK-7 (mTOR associated protein, eak-7 homolog) was identified as a positive activator of mTOR signaling via an alternative mTOR complex. However, the upstream regulation of mEAK-7 in...

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Detalles Bibliográficos
Autores principales: Mendonça, Daniela Baccelli, Nguyen, Joe Truong, Haidar, Fatima, Fox, Alexandra Lucienne, Ray, Connor, Amatullah, Halimah, Liu, Fei, Kim, Jin Koo, Krebsbach, Paul H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753913/
https://www.ncbi.nlm.nih.gov/pubmed/33364499
http://dx.doi.org/10.1016/j.heliyon.2020.e05734