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IFI16 knockdown in primary HIV-1 target cells

IFI16 is an important player of the host intrinsic immune response. Among others, it has been reported to sense intermediate products of HIV-1 reverse transcription in the cytosol and to sequester the transcription factor Sp1 in the nucleus to attenuate viral gene expression. Here, we present three...

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Detalles Bibliográficos
Autores principales: Bosso, Matteo, Bozzo, Caterina Prelli, Volcic, Meta, Kirchhoff, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753938/
https://www.ncbi.nlm.nih.gov/pubmed/33364624
http://dx.doi.org/10.1016/j.xpro.2020.100236