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Ιn vivo imaging of DNA-bound minichromosome maintenance complex in embryonic mouse cortex
The recruitment of the minichromosome maintenance complex (MCM) on DNA replication origins is a critical process for faithful genome duplication termed licensing. Aberrant licensing has been associated with cancer and, recently, with neurodevelopmental diseases. Investigating MCM loading in complica...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753948/ https://www.ncbi.nlm.nih.gov/pubmed/33364622 http://dx.doi.org/10.1016/j.xpro.2020.100234 |