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Selection-driven tumor evolution with public goods leads to patterns of clonal expansion consistent with neutral growth
Cancers are the result of eco-evolutionary processes fueled by heritable phenotypic diversification and driven by environmentally dependent selection. Space represents a key growth-limiting ecological resource, the ability to explore this resource is likely under strong selection. Using agent-based...
Autores principales: | Edwards, Jack, Marusyk, Andriy, Basanta, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753957/ https://www.ncbi.nlm.nih.gov/pubmed/33364589 http://dx.doi.org/10.1016/j.isci.2020.101901 |
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