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TFE3‐PD‐L1 axis is pivotal for sunitinib resistance in clear cell renal cell carcinoma

The microphthalmia of bHLH‐LZ transcription factor (MiT/TFE) family chromosomal translocation or overexpression is linked with a poor prognosis in clear cell renal cell carcinoma (ccRCC) with elevated recurrence and drug resistance, but the molecular mechanism is not fully understood. Here, we inves...

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Detalles Bibliográficos
Autores principales: Guo, Xudong, Li, Ruxia, Bai, Qiulei, Jiang, Shaobo, Wang, Hanbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753981/
https://www.ncbi.nlm.nih.gov/pubmed/33145941
http://dx.doi.org/10.1111/jcmm.16066