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IFN‐γ(+)IL‐17(+)Th17 cells regulate fibrosis through secreting IL‐21 in systemic scleroderma

This study aimed to explore the function of IFN‐γ(+)IL‐17(+)Th17 cells on fibrosis in systemic scleroderma (SSc). Blood and skin samples were collected from 20 SSc cases and 10 healthy individuals. The percentage of IFN‐γ(+)IL‐17(+)Th17 cells was detected using flow cytometry. The in vitro induction...

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Detalles Bibliográficos
Autores principales: Xing, Xiaojing, Li, Anqi, Tan, Hong, Zhou, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753990/
https://www.ncbi.nlm.nih.gov/pubmed/33157566
http://dx.doi.org/10.1111/jcmm.15266