The GENDULF algorithm: mining transcriptomics to uncover modifier genes for monogenic diseases

Modifier genes are believed to account for the clinical variability observed in many Mendelian disorders, but their identification remains challenging due to the limited availability of genomics data from large patient cohorts. Here, we present GENDULF (GENetic moDULators identiFication), one of the...

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Detalles Bibliográficos
Autores principales: Auslander, Noam, Ramos, Daniel M, Zelaya, Ivette, Karathia, Hiren, Crawford, Thomas O., Schäffer, Alejandro A, Sumner, Charlotte J, Ruppin, Eytan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754056/
https://www.ncbi.nlm.nih.gov/pubmed/33438800
http://dx.doi.org/10.15252/msb.20209701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754056/
https://www.ncbi.nlm.nih.gov/pubmed/33438800
http://dx.doi.org/10.15252/msb.20209701

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