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The stiffness‐controlled release of interleukin‐6 by cardiac fibroblasts is dependent on integrin α2β1

Cardiac fibroblasts are able to sense the rigidity of their environment. The present study examines whether the stiffness of the substrate in cardiac fibroblast culture can influence the release of interleukin‐6 (IL‐6), interleukin‐11 (IL‐11) and soluble receptor of IL‐6 (sIL‐6R). It also examines t...

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Detalles Bibliográficos
Autores principales: Gałdyszyńska, Małgorzata, Bobrowska, Justyna, Lekka, Małgorzata, Radwańska, Paulina, Piera, Lucyna, Szymański, Jacek, Drobnik, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754059/
https://www.ncbi.nlm.nih.gov/pubmed/33124775
http://dx.doi.org/10.1111/jcmm.15974