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Cav 1.3 damages the osteogenic differentiation in osteoporotic rats by negatively regulating Spred 2‐mediated autophagy‐induced cell senescence

Cav 1.3 can affect the classical osteoclast differentiation pathway through calcium signalling pathway. Here, we performed cell transfection, real‐time fluorescence quantitative PCR (qPCR), flow cytometry, SA‐β‐Gal staining, Alizarin Red S staining, ALP activity test, immunofluorescence, Western blo...

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Detalles Bibliográficos
Autores principales: Fan, Ping, Pu, Dan, Lv, Xiaohong, Hu, Nan, Feng, Xiuyuan, Hao, Zhiming, Sun, Yining, He, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754063/
https://www.ncbi.nlm.nih.gov/pubmed/33124763
http://dx.doi.org/10.1111/jcmm.15978