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The protective effects of MSC‐EXO against pulmonary hypertension through regulating Wnt5a/BMP signalling pathway

The aim of the study was to explore the mechanism of mesenchymal stem cell‐derived exosomes (MSC‐EXO) to protect against experimentally induced pulmonary hypertension (PH). Monocrotaline (MCT)‐induced rat model of PH was successfully established by a single intraperitoneal injection of 50 mg/kg MCT,...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaohua, Ge, LiLi, Zhang, Shanshan, Wang, Jue, Jiang, Wen, Xin, Qian, Luan, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754064/
https://www.ncbi.nlm.nih.gov/pubmed/33090702
http://dx.doi.org/10.1111/jcmm.16002