USP15 promotes the apoptosis of degenerative nucleus pulposus cells by suppressing the PI3K/AKT signalling pathway

OBJECTIVES: Degenerative disc disease is characterized by an enhanced breakdown of its existing nucleus pulposus (NP) matrix due to the dysregulation of matrix enzymes and factors. Ubiquitin‐specific protease 15 (USP15) is reported to be abnormal in certain human diseases. However, its role in NP de...

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Detalles Bibliográficos
Autores principales: Yu, Bin, Shen, Bin, Ba, Zhaoyu, Liu, Zhonghan, Yuan, Jing, Zhao, Weidong, Wu, Desheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754067/
https://www.ncbi.nlm.nih.gov/pubmed/33135363
http://dx.doi.org/10.1111/jcmm.15971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754067/
https://www.ncbi.nlm.nih.gov/pubmed/33135363
http://dx.doi.org/10.1111/jcmm.15971

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