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USP15 promotes the apoptosis of degenerative nucleus pulposus cells by suppressing the PI3K/AKT signalling pathway
OBJECTIVES: Degenerative disc disease is characterized by an enhanced breakdown of its existing nucleus pulposus (NP) matrix due to the dysregulation of matrix enzymes and factors. Ubiquitin‐specific protease 15 (USP15) is reported to be abnormal in certain human diseases. However, its role in NP de...
Autores principales: | Yu, Bin, Shen, Bin, Ba, Zhaoyu, Liu, Zhonghan, Yuan, Jing, Zhao, Weidong, Wu, Desheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754067/ https://www.ncbi.nlm.nih.gov/pubmed/33135363 http://dx.doi.org/10.1111/jcmm.15971 |
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