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Reduction in flippase activity contributes to surface presentation of phosphatidylserine in human senescent erythrocytes
Mature human erythrocytes circulate in blood for approximately 120 days, and senescent erythrocytes are removed by splenic macrophages. During this process, the cell membranes of senescent erythrocytes express phosphatidylserine, which is recognized as a signal for phagocytosis by macrophages. Howev...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754070/ https://www.ncbi.nlm.nih.gov/pubmed/33103382 http://dx.doi.org/10.1111/jcmm.16010 |