Alpha lipoic acid promotes development of hematopoietic progenitors derived from human embryonic stem cells by antagonizing ROS signals

Antagonism of ROS signaling can inhibit cell apoptosis and autophagy, thus favoring the maintenance and expansion of hematopoietic stem cells. Alpha lipoic acid (ALA), a small antioxidant molecule, affects cell apoptosis by lowering the ROS level. In this study, we show that ALA promoted production...

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Detalles Bibliográficos
Autores principales: Dong, Yong, Bai, Ju, Zhang, Yimeng, Zhou, Ya, Pan, Xu, Li, Xiaohong, Zhou, Qiongxiu, Chen, Yijin, Lai, Mowen, Mao, Bin, Bian, Guohui, Feng, Jia, Xie, Fangxin, Chen, Bo, Nakahata, Tatsutoshi, Zhang, Yonggang, Ma, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cell Development, Differentiation, & Trafficking
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754144/
https://www.ncbi.nlm.nih.gov/pubmed/32640500
http://dx.doi.org/10.1002/JLB.1A0520-179R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754144/
https://www.ncbi.nlm.nih.gov/pubmed/32640500
http://dx.doi.org/10.1002/JLB.1A0520-179R

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