Morphological Profiling Identifies a Common Mode of Action for Small Molecules with Different Targets

Unbiased morphological profiling of bioactivity, for example, in the cell painting assay (CPA), enables the identification of a small molecule's mode of action based on its similarity to the bioactivity of reference compounds, irrespective of the biological target or chemical similarity. This i...

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Detalles Bibliográficos
Autores principales: Schneidewind, Tabea, Brause, Alexandra, Pahl, Axel, Burhop, Annina, Mejuch, Tom, Sievers, Sonja, Waldmann, Herbert, Ziegler, Slava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754162/
https://www.ncbi.nlm.nih.gov/pubmed/32618075
http://dx.doi.org/10.1002/cbic.202000381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754162/
https://www.ncbi.nlm.nih.gov/pubmed/32618075
http://dx.doi.org/10.1002/cbic.202000381

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