Cargando…

Predicting the Substrate Scope of the Flavin‐Dependent Halogenase BrvH

The recently described flavin‐dependent halogenase BrvH is able to catalyse both the bromination and chlorination of indole, but shows significantly higher bromination activity. BrvH was annotated as a tryptophan halogenase, but does not accept tryptophan as a substrate. Its native substrate remains...

Descripción completa

Detalles Bibliográficos
Autores principales: Neubauer, Pia R., Pienkny, Silke, Wessjohann, Ludger, Brandt, Wolfgang, Sewald, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754283/
https://www.ncbi.nlm.nih.gov/pubmed/32645255
http://dx.doi.org/10.1002/cbic.202000444