Zinc modulation of proton currents in a new voltage‐gated proton channel suggests a mechanism of inhibition

The H(V)1 voltage‐gated proton (H(V)1) channel is a key component of the cellular proton extrusion machinery and is pivotal for charge compensation during the respiratory burst of phagocytes. The best‐described physiological inhibitor of H(V)1 is Zn(2+). Externally applied ZnCl(2) drastically reduce...

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Detalles Bibliográficos
Autores principales: Chaves, Gustavo, Bungert‐Plümke, Stefanie, Franzen, Arne, Mahorivska, Iryna, Musset, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754295/
https://www.ncbi.nlm.nih.gov/pubmed/32160407
http://dx.doi.org/10.1111/febs.15291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754295/
https://www.ncbi.nlm.nih.gov/pubmed/32160407
http://dx.doi.org/10.1111/febs.15291

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