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The role of cathepsin D in the pathophysiology of heart failure and its potentially beneficial properties: a translational approach

AIMS: Cathepsin D is a ubiquitous lysosomal protease that is primarily secreted due to oxidative stress. The role of circulating cathepsin D in heart failure (HF) is unknown. The aim of this study is to determine the association between circulating cathepsin D levels and clinical outcomes in patient...

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Detalles Bibliográficos
Autores principales: Hoes, Martijn F., Tromp, Jasper, Ouwerkerk, Wouter, Bomer, Nils, Oberdorf‐Maass, Silke U., Samani, Nilesh J., Ng, Leong L., Lang, Chim C., van der Harst, Pim, Hillege, Hans, Anker, Stefan D., Metra, Marco, van Veldhuisen, Dirk J., Voors, Adriaan A., van der Meer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754332/
https://www.ncbi.nlm.nih.gov/pubmed/31797504
http://dx.doi.org/10.1002/ejhf.1674