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The role of cathepsin D in the pathophysiology of heart failure and its potentially beneficial properties: a translational approach
AIMS: Cathepsin D is a ubiquitous lysosomal protease that is primarily secreted due to oxidative stress. The role of circulating cathepsin D in heart failure (HF) is unknown. The aim of this study is to determine the association between circulating cathepsin D levels and clinical outcomes in patient...
Autores principales: | Hoes, Martijn F., Tromp, Jasper, Ouwerkerk, Wouter, Bomer, Nils, Oberdorf‐Maass, Silke U., Samani, Nilesh J., Ng, Leong L., Lang, Chim C., van der Harst, Pim, Hillege, Hans, Anker, Stefan D., Metra, Marco, van Veldhuisen, Dirk J., Voors, Adriaan A., van der Meer, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754332/ https://www.ncbi.nlm.nih.gov/pubmed/31797504 http://dx.doi.org/10.1002/ejhf.1674 |
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