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Comparison between coagulation factor VIII quantified with one‐stage activity assay and with mass spectrometry in haemophilia A patients: Proof of principle

INTRODUCTION: Haemophilia A is a hereditary bleeding disorder caused by a factor VIII (FVIII) deficiency. As biomarker, FVIII activity is used to classify disease severity and to monitor treatment. The one‐stage clotting assay (OSA) is performed to measure FVIII activity, but OSA's limitations...

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Detalles Bibliográficos
Autores principales: Donners, Anouk A. M. T., van Maarseveen, Erik M., Weetink, Yrea R. J., El Amrani, Mohsin, Fischer, Kathelijn, Rademaker, Carin M. A., Egberts, Toine C. G., Huisman, Albert, Musson, Ruben E. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754357/
https://www.ncbi.nlm.nih.gov/pubmed/32633067
http://dx.doi.org/10.1111/ijlh.13283