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Distinct Mechanisms for Processing Autophagy Protein LC3‐PE by RavZ and ATG4B

Autophagy is a conserved catabolic process involved in the elimination of proteins, organelles and pathogens in eukaryotic cells. Lipidated LC3 proteins that are conjugated to phosphatidylethanolamine (PE) play a key role in autophagosome biogenesis. Endogenous ATG4‐mediated deconjugation of LC3‐PE...

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Detalles Bibliográficos
Autores principales: Yang, Aimin, Pantoom, Supansa, Wu, Yao‐Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754449/
https://www.ncbi.nlm.nih.gov/pubmed/32686895
http://dx.doi.org/10.1002/cbic.202000359