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p53 is associated with high‐risk and pinpoints TP53 missense mutations in mantle cell lymphoma

Survival for patients diagnosed with mantle cell lymphoma (MCL) has improved drastically in recent years. However, patients carrying mutations in tumour protein p53 (TP53) do not benefit from modern chemotherapy‐based treatments and have poor prognosis. Thus, there is a clinical need to identify mis...

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Detalles Bibliográficos
Autores principales: Rodrigues, Joana M., Hassan, May, Freiburghaus, Catja, Eskelund, Christian W., Geisler, Christian, Räty, Riikka, Kolstad, Arne, Sundström, Christer, Glimelius, Ingrid, Grønbæk, Kirsten, Kwiecinska, Anna, Porwit, Anna, Jerkeman, Mats, Ek, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754513/
https://www.ncbi.nlm.nih.gov/pubmed/32748433
http://dx.doi.org/10.1111/bjh.17023