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Thymosin β10 promotes tumor-associated macrophages M2 conversion and proliferation via the PI3K/Akt pathway in lung adenocarcinoma

BACKGROUND: Thymosin β10 (TMSB10) has been reported to play a protumorigenic role in a majority of solid cancers. However, the existence of TMSB10 in immune microenvironment may contribute to the pathogenesis of lung adenocarcinoma has not been previously explored. METHOD: TAMs-associated TMSB10 exp...

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Detalles Bibliográficos
Autores principales: Zeng, Jun, Yang, Xianggui, Yang, Li, Li, Wancheng, Zheng, Yaxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754581/
https://www.ncbi.nlm.nih.gov/pubmed/33349268
http://dx.doi.org/10.1186/s12931-020-01587-7