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Molecular underpinning of intracellular pH regulation on TMEM16F

TMEM16F, a dual-function phospholipid scramblase and ion channel, is important in blood coagulation, skeleton development, HIV infection, and cell fusion. Despite advances in understanding its structure and activation mechanism, how TMEM16F is regulated by intracellular factors remains largely elusi...

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Detalles Bibliográficos
Autores principales: Liang, Pengfei, Yang, Huanghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754671/
https://www.ncbi.nlm.nih.gov/pubmed/33346788
http://dx.doi.org/10.1085/jgp.202012704