Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells

During affinity maturation, germinal center (GC) B cells alternate between proliferation and somatic hypermutation in the dark zone (DZ) and affinity-dependent selection in the light zone (LZ). This anatomical segregation imposes that the vigorous proliferation that allows clonal expansion of positi...

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Detalles Bibliográficos
Autores principales: Pae, Juhee, Ersching, Jonatan, Castro, Tiago B.R., Schips, Marta, Mesin, Luka, Allon, Samuel J., Ordovas-Montanes, Jose, Mlynarczyk, Coraline, Melnick, Ari, Efeyan, Alejo, Shalek, Alex K., Meyer-Hermann, Michael, Victora, Gabriel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754672/
https://www.ncbi.nlm.nih.gov/pubmed/33332554
http://dx.doi.org/10.1084/jem.20201699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754672/
https://www.ncbi.nlm.nih.gov/pubmed/33332554
http://dx.doi.org/10.1084/jem.20201699

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