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A combination of quinidine/mexiletine reduces arrhythmia in dilated cardiomyopathy in two patients with R814W SCN5A mutation

SCN5A gene mutations are described in 2% of patients with dilated cardiomyopathy (DCM) and different rhythm disturbances, including multifocal ectopic Purkinje‐related premature contractions. Recent data indicate that sodium channel blockers are particularly effective monotherapy in carriers of the...

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Detalles Bibliográficos
Autores principales: Zakrzewska‐Koperska, Joanna, Bilińska, Zofia T., Truszkowska, Grażyna T., Franaszczyk, Maria, Elikowski, Waldemar, Warmiński, Grzegorz, Kalin, Katarzyna, Urbanek, Piotr, Bodalski, Robert, Orczykowski, Michał, Szumowski, Łukasz, Płoski, Rafał, Bilińska, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754730/
https://www.ncbi.nlm.nih.gov/pubmed/33084224
http://dx.doi.org/10.1002/ehf2.12993