De Novo Discovery of High-Affinity Peptide Binders for the SARS-CoV-2 Spike Protein

[Image: see text] The β-coronavirus SARS-CoV-2 has caused a global pandemic. Affinity reagents targeting the SARS-CoV-2 spike protein are of interest for the development of therapeutics and diagnostics. We used affinity selection–mass spectrometry for the rapid discovery of synthetic high-affinity p...

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Detalles Bibliográficos
Autores principales: Pomplun, Sebastian, Jbara, Muhammad, Quartararo, Anthony J., Zhang, Genwei, Brown, Joseph S., Lee, Yen-Chun, Ye, Xiyun, Hanna, Stephanie, Pentelute, Bradley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755081/
https://www.ncbi.nlm.nih.gov/pubmed/33527085
http://dx.doi.org/10.1021/acscentsci.0c01309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755081/
https://www.ncbi.nlm.nih.gov/pubmed/33527085
http://dx.doi.org/10.1021/acscentsci.0c01309

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