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De Novo Discovery of High-Affinity Peptide Binders for the SARS-CoV-2 Spike Protein
[Image: see text] The β-coronavirus SARS-CoV-2 has caused a global pandemic. Affinity reagents targeting the SARS-CoV-2 spike protein are of interest for the development of therapeutics and diagnostics. We used affinity selection–mass spectrometry for the rapid discovery of synthetic high-affinity p...
Autores principales: | Pomplun, Sebastian, Jbara, Muhammad, Quartararo, Anthony J., Zhang, Genwei, Brown, Joseph S., Lee, Yen-Chun, Ye, Xiyun, Hanna, Stephanie, Pentelute, Bradley L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755081/ https://www.ncbi.nlm.nih.gov/pubmed/33527085 http://dx.doi.org/10.1021/acscentsci.0c01309 |
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