Identification and quantitation of hinge cysteinylation on endogenous IgG2 antibodies from human serum

Cysteinylation is a post-translational modification (PTM) that occurs when a cysteine residue on a protein forms a disulfide bond with a terminal cysteine molecule. This PTM has been found in the hinge region of several recombinant therapeutic IgG2 antibodies, but the impact of cysteinylation on the...

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Detalles Bibliográficos
Autores principales: Ayalew, Luladey, D’Souza, Alicia D., Chen, Yan, Kim, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755172/
https://www.ncbi.nlm.nih.gov/pubmed/33317401
http://dx.doi.org/10.1080/19420862.2020.1854923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755172/
https://www.ncbi.nlm.nih.gov/pubmed/33317401
http://dx.doi.org/10.1080/19420862.2020.1854923

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