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Identification and quantitation of hinge cysteinylation on endogenous IgG2 antibodies from human serum
Cysteinylation is a post-translational modification (PTM) that occurs when a cysteine residue on a protein forms a disulfide bond with a terminal cysteine molecule. This PTM has been found in the hinge region of several recombinant therapeutic IgG2 antibodies, but the impact of cysteinylation on the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755172/ https://www.ncbi.nlm.nih.gov/pubmed/33317401 http://dx.doi.org/10.1080/19420862.2020.1854923 |