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proABC-2: PRediction of AntiBody contacts v2 and its application to information-driven docking

MOTIVATION: Monoclonal antibodies are essential tools in the contemporary therapeutic armory. Understanding how these recognize their antigen is a fundamental step in their rational design and engineering. The rising amount of publicly available data is catalyzing the development of computational ap...

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Detalles Bibliográficos
Autores principales: Ambrosetti, Francesco, Olsen, Tobias Hegelund, Olimpieri, Pier Paolo, Jiménez-García, Brian, Milanetti, Edoardo, Marcatilli, Paolo, Bonvin, Alexandre M J J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755408/
https://www.ncbi.nlm.nih.gov/pubmed/32683441
http://dx.doi.org/10.1093/bioinformatics/btaa644