IDRMutPred: predicting disease-associated germline nonsynonymous single nucleotide variants (nsSNVs) in intrinsically disordered regions

MOTIVATION: Despite of the lack of folded structure, intrinsically disordered regions (IDRs) of proteins play versatile roles in various biological processes, and many nonsynonymous single nucleotide variants (nsSNVs) in IDRs are associated with human diseases. The continuous accumulation of nsSNVs...

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Detalles Bibliográficos
Autores principales: Zhou, Jing-Bo, Xiong, Yao, An, Ke, Ye, Zhi-Qiang, Wu, Yun-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755418/
https://www.ncbi.nlm.nih.gov/pubmed/32756939
http://dx.doi.org/10.1093/bioinformatics/btaa618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755418/
https://www.ncbi.nlm.nih.gov/pubmed/32756939
http://dx.doi.org/10.1093/bioinformatics/btaa618

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