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IDRMutPred: predicting disease-associated germline nonsynonymous single nucleotide variants (nsSNVs) in intrinsically disordered regions
MOTIVATION: Despite of the lack of folded structure, intrinsically disordered regions (IDRs) of proteins play versatile roles in various biological processes, and many nonsynonymous single nucleotide variants (nsSNVs) in IDRs are associated with human diseases. The continuous accumulation of nsSNVs...
Autores principales: | Zhou, Jing-Bo, Xiong, Yao, An, Ke, Ye, Zhi-Qiang, Wu, Yun-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755418/ https://www.ncbi.nlm.nih.gov/pubmed/32756939 http://dx.doi.org/10.1093/bioinformatics/btaa618 |
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