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Efficient weighted univariate clustering maps outstanding dysregulated genomic zones in human cancers
MOTIVATION: Chromosomal patterning of gene expression in cancer can arise from aneuploidy, genome disorganization or abnormal DNA methylation. To map such patterns, we introduce a weighted univariate clustering algorithm to guarantee linear runtime, optimality and reproducibility. RESULTS: We presen...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755420/ https://www.ncbi.nlm.nih.gov/pubmed/32619008 http://dx.doi.org/10.1093/bioinformatics/btaa613 |