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Proteome profiling and vector yield optimization in a recombinant adeno‐associated virus‐producing yeast model

Recent studies on recombinant adeno‐associated viral (rAAV) vector production demonstrated the generation of infectious viral particles in Saccharomyces cerevisiae. Proof‐of‐concept results showed low vector yields that correlated with low AAV DNA encapsidation rates. In an attempt to understand the...

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Detalles Bibliográficos
Autores principales: Aponte‐Ubillus, Juan Jose, Barajas, Daniel, Sterling, Harry, Aghajanirefah, Ali, Bardliving, Cameron, Peltier, Joseph, Shamlou, Parviz, Roy, Mimi, Gold, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755776/
https://www.ncbi.nlm.nih.gov/pubmed/33166081
http://dx.doi.org/10.1002/mbo3.1136