Megakaryocytic Expansion in Gilteritinib-Treated Acute Myeloid Leukemia Patients Is Associated With AXL Inhibition

Numerous recurrent genetic mutations are known to occur in acute myeloid leukemia (AML). Among these common mutations, Fms-like tyrosine kinase 3 remains as one of the most frequently mutated genes in AML. We observed apparent marrow expansion of megakaryocytes in three out of six patients with Flt3...

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Detalles Bibliográficos
Autores principales: Suknuntha, Kran, Choi, Yoon Jung, Jung, Ho Sun, Majumder, Aditi, Shah, Sujal, Slukvin, Igor, Ranheim, Erik A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756118/
https://www.ncbi.nlm.nih.gov/pubmed/33363015
http://dx.doi.org/10.3389/fonc.2020.585151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756118/
https://www.ncbi.nlm.nih.gov/pubmed/33363015
http://dx.doi.org/10.3389/fonc.2020.585151

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