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LET-Dependent Low Dose and Synergistic Inhibition of Human Angiogenesis by Charged Particles: Validation of miRNAs that Drive Inhibition

Space radiation inhibits angiogenesis by two mechanisms depending on the linear energy transfer (LET). Using human 3D micro-vessel models, blockage of the early motile stage of angiogenesis was determined to occur after exposure to low LET ions (<3 KeV/AMU), whereas inhibition of the later stages...

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Detalles Bibliográficos
Autores principales: Wuu, Yen-Ruh, Hu, Burong, Okunola, Hazeem, Paul, Amber M., Blaber, Elizabeth A., Cheng-Campbell, Margareth, Beheshti, Afshin, Grabham, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756138/
https://www.ncbi.nlm.nih.gov/pubmed/33376971
http://dx.doi.org/10.1016/j.isci.2020.101771