Regulation of human sphingomyelin synthase 1 translation through its 5′‐untranslated region

Bcr‐abl1 oncogene causes a shift in the transcription start site of the SMS1 gene (SGMS1) encoding the sphingomyelin (SM) synthesizing enzyme, sphingomyelin synthase 1 (SMS1). This results in an mRNA with a significantly shorter 5′‐UTR, called 7‐SGMS1, which is translated more efficiently than anoth...

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Detalles Bibliográficos
Autores principales: Daian, Foysal, Esper, Brecken Shenandoah, Ashrafi, Navid, Yu, Gui‐Qin, Luciano, Gabriella, Moorthi, Sitapriya, Luberto, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756225/
https://www.ncbi.nlm.nih.gov/pubmed/33037626
http://dx.doi.org/10.1002/1873-3468.13952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756225/
https://www.ncbi.nlm.nih.gov/pubmed/33037626
http://dx.doi.org/10.1002/1873-3468.13952

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