TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders

Genetic signal detection in genome‐wide association studies (GWAS) is enhanced by pooling small signals from multiple Single Nucleotide Polymorphism (SNP), for example, across genes and pathways. Because genes are believed to influence traits via gene expression, it is of interest to combine informa...

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Detalles Bibliográficos
Autores principales: Chatzinakos, Chris, Georgiadis, Foivos, Lee, Donghyung, Cai, Na, Vladimirov, Vladimir I., Docherty, Anna, Webb, Bradley T., Riley, Brien P., Flint, Jonathan, Kendler, Kenneth S., Daskalakis, Nikolaos P., Bacanu, Silviu‐Alin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756231/
https://www.ncbi.nlm.nih.gov/pubmed/32954640
http://dx.doi.org/10.1002/ajmg.b.32823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756231/
https://www.ncbi.nlm.nih.gov/pubmed/32954640
http://dx.doi.org/10.1002/ajmg.b.32823

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