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Histone demethylase PHF8 drives neuroendocrine prostate cancer progression by epigenetically upregulating FOXA2

Neuroendocrine prostate cancer (NEPC) is a more aggressive subtype of castration‐resistant prostate cancer (CRPC). Although it is well established that PHF8 can enhance prostate cancer cell proliferation, whether PHF8 is involved in prostate cancer initiation and progression is relatively unclear. B...

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Detalles Bibliográficos
Autores principales: Liu, Qiuli, Pang, Jian, Wang, Lin‐ang, Huang, Zhuowei, Xu, Jing, Yang, Xingxia, Xie, Qiubo, Huang, Yiqiang, Tang, Tang, Tong, Dali, Liu, Gaolei, Wang, Luofu, Zhang, Dianzheng, Ma, Qiang, Xiao, Hualiang, Lan, Weihua, Qin, Jun, Jiang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756255/
https://www.ncbi.nlm.nih.gov/pubmed/33009820
http://dx.doi.org/10.1002/path.5557