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Direct β‐ and γ‐C(sp(3))−H Alkynylation of Free Carboxylic Acids
In this study we report the identification of a novel class of ligands for palladium‐catalyzed C(sp(3))−H activation that enables the direct alkynylation of free carboxylic acid substrates. In contrast to previous synthetic methods, no introduction/removal of an exogenous directing group is required...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756274/ https://www.ncbi.nlm.nih.gov/pubmed/32898310 http://dx.doi.org/10.1002/anie.202010784 |