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Aptamer‐Mediated Reversible Transactivation of Gene Expression by Light

The investigation and manipulation of cellular processes with subcellular resolution requires non‐invasive tools with spatiotemporal precision and reversibility. Building on the interaction of the photoreceptor PAL with an RNA aptamer, we describe a variation of the CRISPR/dCAS9 system for light‐con...

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Detalles Bibliográficos
Autores principales: Renzl, Christian, Kakoti, Ankana, Mayer, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756287/
https://www.ncbi.nlm.nih.gov/pubmed/32865316
http://dx.doi.org/10.1002/anie.202009240