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Aptamer‐Mediated Reversible Transactivation of Gene Expression by Light
The investigation and manipulation of cellular processes with subcellular resolution requires non‐invasive tools with spatiotemporal precision and reversibility. Building on the interaction of the photoreceptor PAL with an RNA aptamer, we describe a variation of the CRISPR/dCAS9 system for light‐con...
Autores principales: | Renzl, Christian, Kakoti, Ankana, Mayer, Günter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756287/ https://www.ncbi.nlm.nih.gov/pubmed/32865316 http://dx.doi.org/10.1002/anie.202009240 |
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