Discovery and Biosynthesis of Bolagladins: Unusual Lipodepsipeptides from Burkholderia gladioli Clinical Isolates

Two Burkholderia gladioli strains isolated from the lungs of cystic fibrosis patients were found to produce unusual lipodepsipeptides containing a unique citrate‐derived fatty acid and a rare dehydro‐β‐alanine residue. The gene cluster responsible for their biosynthesis was identified by bioinformat...

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Detalles Bibliográficos
Autores principales: Dashti, Yousef, Nakou, Ioanna T., Mullins, Alex J., Webster, Gordon, Jian, Xinyun, Mahenthiralingam, Eshwar, Challis, Gregory L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756342/
https://www.ncbi.nlm.nih.gov/pubmed/32780452
http://dx.doi.org/10.1002/anie.202009110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756342/
https://www.ncbi.nlm.nih.gov/pubmed/32780452
http://dx.doi.org/10.1002/anie.202009110

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