An Organometallic Gold(I) Bis‐N‐Heterocyclic Carbene Complex with Multimodal Activity in Ovarian Cancer Cells

The organometallic Au(I) bis‐N‐heterocyclic carbene complex [Au(9‐methylcaffeine‐8‐ylidene)(2)](+) (AuTMX(2)) was previously shown to selectively and potently stabilise telomeric DNA G‐quadruplex (G4) structures. This study sheds light on the molecular reactivity and mode of action of AuTMX(2) in th...

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Detalles Bibliográficos
Autores principales: Meier‐Menches, Samuel M., Neuditschko, Benjamin, Zappe, Katja, Schaier, Martin, Gerner, Marlene C., Schmetterer, Klaus G., Del Favero, Giorgia, Bonsignore, Riccardo, Cichna‐Markl, Margit, Koellensperger, Gunda, Casini, Angela, Gerner, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756355/
https://www.ncbi.nlm.nih.gov/pubmed/32902006
http://dx.doi.org/10.1002/chem.202003495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756355/
https://www.ncbi.nlm.nih.gov/pubmed/32902006
http://dx.doi.org/10.1002/chem.202003495

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