Cargando…

An Organometallic Gold(I) Bis‐N‐Heterocyclic Carbene Complex with Multimodal Activity in Ovarian Cancer Cells

The organometallic Au(I) bis‐N‐heterocyclic carbene complex [Au(9‐methylcaffeine‐8‐ylidene)(2)](+) (AuTMX(2)) was previously shown to selectively and potently stabilise telomeric DNA G‐quadruplex (G4) structures. This study sheds light on the molecular reactivity and mode of action of AuTMX(2) in th...

Descripción completa

Detalles Bibliográficos
Autores principales: Meier‐Menches, Samuel M., Neuditschko, Benjamin, Zappe, Katja, Schaier, Martin, Gerner, Marlene C., Schmetterer, Klaus G., Del Favero, Giorgia, Bonsignore, Riccardo, Cichna‐Markl, Margit, Koellensperger, Gunda, Casini, Angela, Gerner, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756355/
https://www.ncbi.nlm.nih.gov/pubmed/32902006
http://dx.doi.org/10.1002/chem.202003495

Ejemplares similares