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An Organometallic Gold(I) Bis‐N‐Heterocyclic Carbene Complex with Multimodal Activity in Ovarian Cancer Cells
The organometallic Au(I) bis‐N‐heterocyclic carbene complex [Au(9‐methylcaffeine‐8‐ylidene)(2)](+) (AuTMX(2)) was previously shown to selectively and potently stabilise telomeric DNA G‐quadruplex (G4) structures. This study sheds light on the molecular reactivity and mode of action of AuTMX(2) in th...
Autores principales: | Meier‐Menches, Samuel M., Neuditschko, Benjamin, Zappe, Katja, Schaier, Martin, Gerner, Marlene C., Schmetterer, Klaus G., Del Favero, Giorgia, Bonsignore, Riccardo, Cichna‐Markl, Margit, Koellensperger, Gunda, Casini, Angela, Gerner, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756355/ https://www.ncbi.nlm.nih.gov/pubmed/32902006 http://dx.doi.org/10.1002/chem.202003495 |
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